I7P-MC-DSAG Ulcerative Colitis Study

An adaptive, dose-ranging, Phase 2 study of eltrekibart and mirikizumab for the treatment of adult patients with moderately to severely active ulcerative colitis

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Eltrekibart is a humanized monoclonal antibody that acts on pathways that modulate neutrophil migration and angiogenesis. Neutrophils are critical to the pathogenesis of ulcerative colitis.
Eltrekibart’s unique and potentially complementary mechanism provides the rationale for studying the treatment alone and in combination with mirikizumab.
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